Table 2.

Duke Activity Status Index in Predicting Future Risk of 90-Day Death From Any Cause

	Univariable Analyses			Multivariable Analysis
	HR	95% CI	P Value	HR	95% CI	P Value
Age (y)	1.034	1.015-1.054	0.001	1.016	0.994-1.038	0.158
Female	0.578	0.354-0.944	0.028	0.481	0.289-0.802	0.005
Log-BUN (mmol/L)	2.533	1.719-3.734	<0.001	1.337	0.829-2.155	0.233
Hemoglobin (g/L)	0.974	0.964-0.983	<0.001	0.982	0.972-0.993	0.001
Log-NT-proBNP (ng/L)	1.407	1.226-1.616	<0.001	1.182	0.992-1.408	0.062
Beta-blockers	1.129	0.717-1.776	0.601	0.680	0.426-1.086	0.106
DASI fourth quartilea	Reference
DASI third quartileb	1.310	0.499-3.442	0.583	0.934	0.352-2.480	0.892
DASI second quartilec	2.897	1.225-6.852	0.015	1.874	0.779-4.511	0.161
DASI first quartiled	5.654	2.525-12.662	<0.001	3.717	1.629-8.482	0.002

Unadjusted and adjusted Cox regression analyses with patients (n = 1,019) stratified according to DASI into quartiles and referenced to fourth quartile. Adjustments made for age (y), sex, natural log-transformed BUN (mmol/L), hemoglobin level (g/L), natural log of NT-proBNP (ng/L) concentrations at presentation and intake of beta-blockers on admission.

BUN = blood urea nitrogen; CI = confidence interval; DASI = Duke Activity Status Index; HR = hazard ratio; NT-proBNP = N-terminal pro-B-type natriuretic peptide.

^aHigh functional exercise capacity (fourth quartile): DASI 40.45 to 52.95 (n = 251).

^bModerately high functional exercise capacity (third quartile): DASI 24.95 < 40.45 (n = 268).

^cModerately low functional exercise capacity (second quartile): DASI 15.45 < 24.95 (n = 248).

^dLow functional exercise capacity (first quartile): DASI 0 < 15.45 (n = 252).