Table 3.
Conventional Cardiac Magnetic Resonance Imaging Measurements in Patients With Heart Failure With Preserved Ejection Fraction
| Women (n = 25) | Men (n = 9) | P Value | |
|---|---|---|---|
| CMR – right ventricle | |||
| RV EDV (mL) | 110.5 (97.8 to 134.8) | 164.3 (145.4 to 209.8) | <0.001 |
| RV EDV (mL/m2 BSA) | 59.9 (53.3 to 69.6) | 77.1 (69.9 to 89.5) | <0.001 |
| RV ESV (mL) | 33.7 (28.6 to 42.6) | 60.7 (46.5 to 74.6) | <0.001 |
| RV ESV (mL/m2 BSA) | 19.2 (15.8 to 21.6) | 27.6 (22.2 to 33.7) | <0.001 |
| RV SV (mL) | 73.0 (67.4 to 98.7) | 101.0 (89.9 to 137.8) | 0.005 |
| RV SV (mL/m2 BSA) | 40.5 (37.4 to 49.2) | 48.1 (45.1 to 57.2) | 0.072 |
| RV EF (%) | 68.4 (63.8 to 74.6) | 65.1 (58.0 to 68.3) | 0.050 |
| CMR – left ventricle | |||
| LV Mass (g/m2 BSA) | 53.9 (50.7 to 60.2) | 67.7 (65.5 to 77.2) | 0.001 |
| LV EDV (mL) | 120.5 (105.4 to 144.6) | 160.3 (139.7 to 204.4) | <0.001 |
| LV EDV (mL/m2 BSA) | 64.9 (56.2 to 73.9) | 75.2 (68.9 to 93.6) | 0.008 |
| LV ESV (mL) | 34.1 (26.7 to 45.7) | 58.6 (44.0 to 67.3) | <0.001 |
| LV ESV (mL/m2 BSA) | 17.0 (14.2 to 24.4) | 25.8 (20.4 to 32.0) | 0.009 |
| LV SV (mL) | 89.2 (77.4 to 101.3) | 114.2 (97.9 to 133.8) | 0.005 |
| LV SV (mL/m2 BSA) | 48.5 (42.0 to 53.8) | 51.9 (45.8 to 60.9) | 0.14 |
| LV EF (%) | 73.4 (67.1 to 76.9) | 66.8 (62.0 to 74.6) | 0.12 |
| GLS (%) | −17.3 (−19.1 to −16.3) | −17.9 (−19.2 to −15.0) | 0.818 |
| CMR – left atrium | |||
| LAVI (mL/m2) | 46.7 (36.1 to 55.1) | 51.0 (39.7 to 69.1) | 0.316 |
| LA min volume rest (mL) | 42.3 (33.9 to 53.4) | 56.1 (45.0 to 76.7) | 0.048 |
| LA min volume stress (mL) | 49.0 (38.6 to 65.8) | 56.3 (49.6 to 90.4) | 0.224 |
| LA min volume reserve (mL) | 6.7 (2.4 to 12.6) | 4.4 (−4.3 to 11.3) | 0.281 |
| LA max volume rest (mL) | 62.8 (52.7 to 77.9) | 88.8 (72.7 to 103.6) | 0.013 |
| LA max volume stress (mL) | 72.1 (56.8 to 90.7) | 100.0 (77.5 to 111.0) | 0.023 |
| LA max volume reserve (mL) | 8.5 (2.8 to 13.0) | 8.4 (−1.1 to 13.8) | 0.929 |
Values are median (IQR) (and were compared using the Mann-Whitney U test). Conventional CMR measurements in patients with HFpEF as defined by right heart catheterization. Data are presented according to patients’ sex. Bold values indicate statistical significance below 0.05.
BSA = body surface area; EDV/ESV = end-diastolic volume/end-systolic volume; EF = ejection fraction; GLS = global longitudinal strain; LA = left atrium; LAVI = left atrial volume index; LV/RV = left/right ventricle; SV = stroke volume.