Table 4.
Long-Term Mortality Following Coronary Artery Stenting by Preterm Delivery (N = 5,766)
| Preterm Delivery History Events/Person Years | No Preterm Delivery 204/25,443 | Ever Preterm Delivery 59/4,916 |
Subgroups of Preterm Delivery | ||||
|---|---|---|---|---|---|---|---|
| (n = 963) | |||||||
| Late Preterm Delivery 38/3,305 |
Early Preterm Delivery 21/1,611 |
||||||
| HR (95% CI) | P Value | HR (95% CI) | P Value | HR (95% CI) | P Value | ||
| Model I | 1.00 (reference) | 1.63 (1.22-2.18) | 0.001 | 1.52 (1.08-2.15) | 0.02 | 1.88 (1.20-2.95) | 0.006 |
| Model II | 1.00 (reference) | 1.59 (1.19-2.14) | 0.002 | 1.50 (1.06-2.13) | 0.02 | 1.80 (1.14-2.84) | 0.01 |
| Model III | 1.00 (reference) | 1.38 (1.02-1.85) | 0.04 | 1.30 (0.92-1.85) | 0.14 | 1.53 (0.97-2.43) | 0.07 |
Model I includes a history of preterm delivery; age at the index coronary artery stenting (continuous). Model II additionally includes procedure type (PCI, PCI ad hoc); indication for coronary artery stenting (STEMI, NSTEMI, unstable coronary artery disease, stable coronary artery disease, other); year of procedure (2006-2009, 2010-2013, 2014-2017); number of vessels treated (1, ≥2); number of stents (1, 2, ≥3); multiple vessel disease (yes/no); drug-eluting stent (yes/no); left main stem treated or left anterior descending artery treated (yes/no); right coronary artery treated (yes/no); left circumflex coronary artery treated (yes/no); any other vessel treated (yes/no). Model III additionally includes diabetes (yes/no); smoking (never smoker, ex-smoker, current smoker); hypertension (yes/no); dyslipidemia (yes/no); prior MI (yes/no). Results from a proportional hazards regression, multiple imputation analysis. Median follow-up duration: 4.90 years (IQR: 2.42-7.93 years).
CI = confidence interval; HR = hazard ratio; MI = myocardial infarction; NSTEMI = non-ST-segment elevation myocardial infarction; PCI = percutaneous coronary intervention; STEMI = ST-segment elevation myocardial infarction.