Table 2.
Comparison of characteristics between EBV-Naïve and EBV-exposed patients with IBD
| Patient characteristics | EBV-Naïve (n=25) | EBV-exposed (n=125) | P |
|---|---|---|---|
| Baseline characteristics | |||
| Age (years), mean (SD) | 26 (8.49) | 31.2 (12.9) | 0.02 |
| Age groups, n (%) | 0.17 | ||
| <14 years of age | 0 | 2 (1.6) | |
| 14-40 years of age | 23 (92) | 97 (77.6) | |
| >40 years of age | 2 (8) | 26 (20.8) | |
| Male sex, n (%) | 12 (48) | 70 (56) | 0.46 |
| Follow-up (months), mean (SD) | 47.9 (46.3) | 52.8 (51.3) | 0.64 |
| Disease characteristics | |||
| Disease type, n (%) | 0.74 | ||
| Crohn’s disease | 18 (72) | 94 (75.2) | |
| Ulcerative colitis | 7 (28) | 31 (24.8) | |
| Bowel resection, n (%) | 11 (44) | 70 (56) | 0.27 |
| Presence of extraintestinal manifestations, n (%) | 7 (28) | 36 (28.8) | 0.94 |
| Stricturing/Penetrating Crohn’s disease, n (%) | 15 (83.3) | 78 (82.9) | 0.97 |
| Perianal Crohn’s disease, n (%) | 6 (33.3) | 38 (40.4) | 0.57 |
EBV: Epstein-Barr virus; SD: Standard deviation