Figure 4.
Potential benefits of moderate (5-10%) weight loss in high risk patients with cluster of atherothrombotic, pro-inflammatory metabolic abnormalities associated with hypertriglyceridaemic waist. Weight loss in abdominally obese patients is associated with selective mobilisation of diabetogenic and atherogenic visceral adipose tissue, even 5-10% weight loss is associated with preferential mobilisation of visceral adipose tissue, leading to simultaneous improvement in all metabolic markers of coronary heart disease risk. Thus simultaneous metabolic improvements associated with mobilisation of visceral adipose tissue may contribute substantially to reduced risk of acute coronary event in high risk patients