FIGURE 2.

(A) qPCR CD13 mRNA expression of SH-SY5Y cells−/+ 10 μM ATM inhibition treatment for 16 h, normalised to B-actin (n = 3), SEM error bars, unpaired t-test with Welch’s correction; (B) qPCR CD13 mRNA expression of AT-WT and AT-/- cell lines, normalised to B-actin (n = 3), SEM error bars, unpaired t-test. (C) CD13 protein expression following 6h treatment with 10 μM ATMi and/or proteasome inhibitor MG-132 in AT-WT cells (D) which was then quantified and analysed with one-way ANOVA (n = 3), *p < 0.05. (E) CD13 co-immunoprecipitation in SH-SY5Y cells, blotting for ATM. No interaction detected.