Figure 1.

Overview of our method for determining territorial CVR. Computational domains of the anterior and posterior parts of the circle of Willis are segmented from CTA data, and to them we apply the measured flow rates and MAP. This subject has a right posterior communicating artery, connecting the anterior and posterior parts of the circle of Willis (flow indicated by orange arrows). CFD is then used to compute the perfusion pressure in the circle of Willis given these conditions. The resulting perfusion pressure, in combination with the flow rates along each outflow branch (blue arrows), allows for computing territorial CVR, i.e. the lumped resistance downstream of each cerebral artery.