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. 2024 Jun 12;15:1400641. doi: 10.3389/fimmu.2024.1400641

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Copyright © 2024 Georgieva, Diddens, Friedrich, Lepennetier, Brand and Lehmann-Horn

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmap representing differentially expressed genes (DEGs) between mELT from control treated and CSF from control treated mice for each cell type. Gene analysis was conducted only for cell counts >50. Thus, not all cell types are shown. The top 10 up- and downregulated genes in mELT from control treated mice when compared to CSF from control treated mice are shown. Genes were ranked according to average log2 fold-change (avg_log 2FC). Positive avg_log 2FC represent upregulated genes in mELT from control treated mice (green), negative values correspond to downregulated genes (blue).