FIG. 2.

Plasma anti-HSV activity and partial reversal by CVF. Plasma was prepared from athymic rats 48 h after intraperitoneal administration of CVF (or carrier) as detailed in Materials and Methods. After serial dilutions, it was mixed with oncolytic HSV before it was added onto Vero cells. Values represent the mean titer of virus from triplicate dishes. Controls, consisting of virus preincubated with HBSS for the same times before addition onto plates, did not show a reduction in mean titer (data not shown). Error bars represent the standard error of the mean. If not shown, then the error bars were too small to graph.