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. 2024 May 8;19(2):135–142. doi: 10.5114/pg.2024.139426

Table II.

Comparison between the 2 studied groups according to outcome and adverse events

Parameter Group A (n = 200) Group B (n = 200) χ2 P-value
Outcome
Urea breath test:
Success rate 172 (86%) 149 (74.5%) 8.344* 0.004*
Failure rate 28 (14%) 51 (25.5%)
Adverse events:
Diarrhoea 8 (4%) 11 (5.5%) 0.497 0.481
Vomiting/nausea 7 (3.5%) 13 (6.5%) 1.895 0.169
Constipation 4 (2%) 7 (3.5%) 0.841 0.359
Abdominal bloating 7 (3.5%) 7 (3.5%) 0.000 1.000
Abdominal pain 7 (3.5%) 6 (3%) 0.080 0.778
Taste disturbance 5 (2.5%) 9 (4.5%) 1.184 0.276
Stomatitis 4 (2%) 7 (3.5%) 0.841 0.359
Rash 4 (2%) 10 (5%) 2.665 0.103

χ2 – Chi-square test, p – p-value for comparing between the studied groups. *Statistically significant at p ≤ 0.05. Group A – vonoprazan-based regimen, Group B – PPI-based regimen.