TABLE 1.

Mutation of the HIV-1 integrase

Mutant	Nucleotide change	Amino acid change
T66A	4425aca→Gcaa	66Thr→Alab
T93A	4506aca→Gca	93Thr→Ala
T125A	4602aca→Gca	125Thr→Ala
Y143G	4656tac→GGG	143Tyr→Gly
K186Q	4785aaa→Caa	186Lys→Gln
G189R/K211N	4794ggg→Agg/4860aaa→aaC	189Gly→Arg/211Lys→Asn
ΔKRK	4785aaaagaaaa→deletion	186LysArgLys→deletion
S195A	4812agt→GCt	195Ser→Ala
S283A	5076agt→GCt	283Ser→Ala

^aAltered nucleotides are indicated by capital letters. Positions of nucleotide are numbered according to the NL43 sequences. 

^bNumbers refer to amino acid residues of NL43 IN.