Table 3.

Gastrointestinal mucositis assessment in clinical practice.

	Clinical setting
	Standard chemotherapy	Pelvic radiotherapy	HSCT	Targeted agents	Immunotherapy
Recommended tool for clinician assessment	WHO CTCAE	WHO CTCAE	Bristol stool chart	Bristol stool chart	Bristol stool chart
Frequency of assessment	First day of each cycle and at any clinic visit/telehealth appointment (especially when symptoms present)	3-weekly	Daily (if in-patient) Weekly (if feasible in outpatient setting)	Monthly (at each cycle or clinic visit/telehealth appointment)	Monthly (at each cycle or clinic visit/telehealth appointment)
Recommended PROM	PRO-CTCAE	PRO-CTCAE	PRO-CTCAE questions or OMDQ plus diarrhea questions may be suggested	No questionnaire specifically validated, suggestion for PRO-CTCAE use	No questionnaire specifically validated, suggestion for PRO-CTCAE use
Frequency of assessment	Weekly	Weekly	Daily if inpatient Weekly if outpatient	At each cycle or clinic visit/telehealth appointment	At each cycle or clinic visit/telehealth appointment
Biomarkers to consider	No biomarkers recommended	Plasma citrulliine	No biomarkers recommended	No biomarkers recommended	No biomarkers recommended