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. 2024 May 27;13(6):492. doi: 10.3390/antibiotics13060492

Table 4.

Toxicological test results of halicin.

Experiments Results
Oral acute toxicity test LD50 was 1274.90 mg/kg b.w.
Intraperitoneal injection acute toxicity test LD50 was 36.84 mg/kg b.w.
Ames test No significant difference in the average number of the four Salmonella typhimurium test strains compared to the negative control group
Mouse sperm abnormality test No significant difference between the dose group and the negative control group (p > 0.05)
Chromosomal aberration test in bone marrow cells No significant difference between the dose group and the negative control group (p > 0.05)
Bone marrow micronucleus test No significant difference between the dose group and the negative control group (p > 0.05)