Table 1.
Pharmacological activities.
| Activities | Measurements | Flx | Dlx | Mir |
|---|---|---|---|---|
| Viability | MTT | + | ++ | ++ |
| Antioxidant effects |
ROS | + | ++ | + |
| Mito-ROS | + | ++ | ++ | |
| Phospholipid peroxidation | + | + | + | |
| Activation of antioxidative enzyme activity | HO-1 | − | + | − |
| Mn-SOD | + | + | + |
++: strong intensity reaction, +: weak intensity reaction, −: no change. MTT, 3-(4, 5-dimethylthiazoyl-2-yl)-2-5, diphenyltetrazolium bromide; ROS, reactive oxygen species; mito-ROS, mitochondrial-ROS; HO-1, heme oxygenase 1; MnSOD, manganese superoxide dismutase; Flx, fluoxetine; Dlx, duloxetine; Mir, mirtazapine.