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. 2024 May 27;12(6):1185. doi: 10.3390/biomedicines12061185

Table 2.

Essential oils from plant species and their pharmacological mechanisms on diabetes.

Plant Species (Family) Major Compounds from Essential Oils Pharmacological Action References
Citrus × sinensis (L.) Osbeck (Rutaceae)
and
Citrus limon (L.) Burm. f. (Rutaceae)
D-Limonene
C. sinensis: 92.14%
C. limon: 53.07%
The EO inhibited α-amylase and α-glucosidase activities [220,221]
62 species from the families: Lauraceae, Myristicaceae, Myrtaceae, Oleaceae, Pinaceae, Piperaceae, Poaceae, Rosaceae, Rutaceae, Santalaceae, Verbenaceae, and Zingiberaceae - In vitro α-amylase inhibitory potentials were obtained after the evaluation of Eucalyptus radiata, Laurus nobilis, and Myristica fragrans EOs. [222]
Syzygirum aromaticum L. (Myrtaceae) Eugenol There was a significant decline in blood glucose levels, total cholesterol, xanthine oxidase, antioxidant activities, and it was a potent α-amylase inhibitor [223]
Ocimum basilicum L. (Lamiaceae) Linalool, methyl estragole, methyl cinnamate, and methyl chavicol Ocimum basilicum essential oil had a strong α-amylase inhibitory activity [224]
Serevenia buxifolia (Poir.) Ten. (Rutaceae) β-caryophyllene (32.5%) and elixene (9.8%) Antidiabetic potential by inhibiting the enzymes α-amylase and α-glucosidase [225]
Kaempferia galanga (L.) (Zingiberaceae) Ethyl p-methoxycinnamate: 66.39% Antidiabetic activity using α-amylase inhibitory activity assay [226]
Dracocephalum heterophyllum Benth. (Lamiaceae) - Antidiabetic potential by inhibiting the enzymes α-amylase and α-glucosidase [227]
Mentha suaveolens “Variegata” (Labiatae) (MSEO);
Lavandula stoechas L. (Lamiaceae) (LSEO);
Ammi visnaga (L.) Lam. (Apiaceae) (AVEO)
MSEO: fenchone (29.77%) and camphor (24.90%)
LSEO: piperitenone oxide (74.55%)
AVEO: linalool (38.24%)
Antidiabetic action by inhibiting the enzymes α-amylase and α-glucosidase [228]
Hypericum scabrum L. (Clusiaceae) - The administration of Hypericum scabrum L. essential oil caused an increase in the level of GSH, GPx, SOD, and CAT activities and there was a decrease in the levels of MDA [229]