Fig. 2.

Effect of different variables on plasma pTau₂₁₇, pTau₁₈₁, Aβ_1–42/Aβ_1–40 and pTau₂₁₇/ Aβ_1–42. Dots and bars represent the standardized beta coefficients of each variable in a multivariate regression model. Lines represent the 95% confidence interval for each standardized beta coefficient. Red vertical dashed lines indicate a null effect. We can see the effect size of A positivity adjusted by other variables. pTau₂₁₇: phosphorylated tau 217. pTau₁₈₁: phosphorylated tau 181. Aβ_1–42: Amyloid β_1–42. Aβ_1–40: Amyloid β_1–40. MCI: mild cognitive impairment. VRF: vascular risk factors. eGFR: estimated glomerular filtration rate