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. 2024 Jun 4;13(6):692. doi: 10.3390/antiox13060692

Table 4.

Stratification meta-analysis of data on individual phenolic compound concentrations according to the type of stevia extract.

Type of Extract Compound Effect Size
(mg CGAE/g dry sample)
CI 95% Number of Studies
Aqueous 3-caffeoylquinic acid 2.25 1.24, 3.26 5
3,4-dicaffeoylquinic acid 2.64 1.16, 4.11 5
3,5-dicaffeoylquinic acid 50.53 25.21, 75.82 5
4-caffeoylquinic acid 11.85 6.09, 17.60 5
4,5-dicaffeoylquinic acid 18.69 4.73, 32.63 5
5-caffeoylquinic acid 1.65 0.69, 2.58 5
5-coumaroyl quinic acid 0.07 0.05, 0.09 5
caffeoyl shikimic acid 0.36 0.12, 0.59 5
Compound Effect Size
(mg/g dry sample)
CI 95% Number of Studies
Hydroalcoholic 3-caffeoylquinic acid 2.91 0.70, 5.11 4
Organic 4,5-dicaffeoylquinic acid 13.15 9.20, 17.11 5
5-caffeoylquinic acid 23.39 19.44, 27.34 5

CGAE: chlorogenic acid equivalents; CI 95%: 95% confidence interval.