Table 1.

Preoperative surgical risk models for patients with cirrhosis.

A. Scores used for predicting mortality in general surgery.
Preoperative Risk Model	Variables	Original Function	Group/Score	Reported Outcome
CTP	Ascites Encephalopathy INR Albumin Bilirubin	Guide selection of patients for portosystemic shunt. Predict mortality in cirrhotic patients.	Class A (5–6 points)	Survival: >15 years Perioperative mortality: 10%
			Class B (7–9 points)	Survival: Transplant referral Perioperative mortality: 30%
			Class C (10–15 points)	Survival: 1–3 years Perioperative mortality: 82%
MELD	INR Serum creatinine Serum bilirubin	Predict 30-day mortality after TIPS	≤9 10–19 20–29 30–39 ≥40	1.9% 6% 19.6% 52.6% 71.3%
MRS	MELD ASA class Age	Predict short- and long-term mortality after elective surgery in cirrhotic patients	Calculated score	Mortality prediction varies based on combined variables
VOCAL-Penn Model	Age Serum albumin Serum bilirubin Platelet count BMI NAFLD ASA class Surgery type	Predict postoperative 30-, 90-, 180-day mortality after specific operations	Calculated score	Mortality prediction based on surgery type and combined variables
B. Scores used for predicting fibrosis stage.
Fibrosis Score Model	Variables	Original Function	Score	Reported Outcome
FIB-4	Age AST ALT Platelet count	Assess liver fibrosis in patients with NAFLD	<1.45 1.45–3.25 >3.25	Fibrosis stage: 0–1 2–3 4–6
Forns Score	Age GGT Cholesterol Platelet count	Identify liver fibrosis in chronic hepatitis C	<4.21 >6.9	Absence significant fibrosis Presence significant fibrosis
C. Scores used for predicting mortality after liver surgery.
Preoperative Risk Model	Variables	Original Function	Score	Reported Outcome
ALBI	Serum bilirubin Serum albumin	Predict overall survival after hepatectomy for HCC	≤−2.6 >−2.6 to ≤−1.39 >−1.39	Median Survival 18.5–85.6 months 5.3–46.5 months 2.3–15.5 months
APRI + ALBI	Serum bilirubin Serum albumin AST Platelet count	Predict post-hepatectomy liver dysfunction and associated 30-day mortality	Calculated score	Post-hepatectomy liver dysfunction and associated 30-day mortality

CTP, Child–Turcotte–Pugh; MELD, model for end-stage liver disease; MRS, Mayo risk score; VOCAL-Penn, Veterans outcomes and costs associated with liver disease; FIB-4, Fibrosis-4; ALBI, albumin-bilirubin score; INR, international normalized ratio; ASA, American society of anesthesiologists; BMI, body mass index; NAFLD, non-alcoholic fatty liver disease; AST, aspartate aminotransferase; ALT, alanine aminotransferase; GGT, gamma-glutamyl transferase; APRI, aspartate aminotransferase/platelet ratio index; TIPS, transjugular intrahepatic portosystemic shunt; HCC, hepatocellular carcinoma.