Structures of recombinant viruses. The genome of virus RM4072 and the prototype (P), inverted-long (IL), and inverted-short (IS) isomers of RM4070 are shown. Hatched boxes represent C- and X-terminal sequences inserted within the genome to generate internal repeats, and double-ended arrows at the top delineate long and short segments created by the repeats. The relative orientations of the repeats are indicated by arrows over the C and X boxes. Sequences contained in hybridization probes are indicated by diagonally hatched bars (probe 1), solid black bars (probe 2), or vertically hatched bars (probe 3). Ectopic terminal (T) and junction (J) MluI (m) and SacI (s) fragments are indicated, with their predicted sizes (in kilobases) shown in parentheses.