Table 3.
ROC analysis of miR-21 expression for distinction among the study subgroups.
| Parameter | Compared Groups | AUC (95% CI) |
Cut-off | Sensitivity (95% CI) |
Specificity (95% CI) |
p Value |
|---|---|---|---|---|---|---|
| miR-21 ΔCt |
group 1 vs. control group | 0.50 (0.36–0.64) |
−0.99 | 100% (89.85–100%) |
3.03% (0.15–15.32%) |
0.99 |
| group 2 vs. control group | 0.68 (0.51–0.85) |
−0.29 | 35.29% (17.31–58.70%) |
96.97% (84.68–99.84%) |
0.03 | |
| group 1 vs. group 2 | 0.69 (0.52–0.85) |
−0.06 | 88.24% (73.38–95.33%) |
41.18% (21.61–63.99%) |
0.02 | |
| miR-21 2−ΔΔCt |
group 1 vs. control group | 0.50 (0.36–0.64) |
0.82 | 100% (89.57–100%) |
8.82% (3.04–22.96%) |
0.99 |
| group 2 vs. control group | 0.68 (0.51–0.85) |
0.92 | 96.97% (84.68–99.84%) |
41.18% (21.61–63.99%) |
0.03 | |
| group 1 vs. group 2 | 0.69 (0.52–0.85) |
0.92 | 88.24% (73.38–95.33%) |
41.18% (21.61–63.99%) |
0.02 |