Table 1.
Characteristics of patients with AIS by α-HBDH grouping
| Characteristics | All (n = 204) | α-HBDHa | t/χ2 | P | |
|---|---|---|---|---|---|
| α-HBDB ≤ 180 (n = 159) | α-HBDB > 180 (n = 45) | ||||
| Median age (IQR)—years | 67.0 (59.0–82.0) | 66.0 (58.0, 80.0) | 79.0 (67.0, 85.0) | 10.791 | 0.001 |
| Female—no. (%) | 60 (29.4) | 35 (21.6) | 25 (59.5) | 23.099 | 0.000 |
| Median OMTb (IQR)—hours | 12.0 (4.0–24.0) | 12.0 (4.5, 24.0) | 12.0 (4.0, 48.0) | 0.31 | 0.861 |
| Median systolic pressure (IQR)—mmHg | 154.0 (138.0–173.5) | 154.0 (140.0, 174.0) | 154.5 (135.0, 172.0) | 0.344 | 0.557 |
| Median diastolic pressure (IQR) -mmHg | 89.0 (78.0–102.0) | 88.50 (78.0, 101.0) | 89.0 (78.0, 103.0) | 0.162 | 0.688 |
| bNIHSSc ≤ 4—no. (%) | 158 (77.5) | 145 (89.5) | 13 (31.0) | 65.477 | 0.000 |
| Medical history—no. (%) | |||||
| Hypertension | 174 (85.3) | 138 (85.2) | 36 (85.7) | 0.07 | 0.931 |
| Diabetes mellitus | 110 (53.9) | 84 (51.9) | 26 (61.9) | 1.357 | 0.244 |
| Hypercholesterolemia | 182 (89.2) | 143 (88.3) | 39(92.9) | 0.729 | 0.393 |
| Atrial fibrillation | 27 (13.2) | 15 (9.3) | 12 (28.6) | 10.832 | 0.001 |
| Prior ischemic stroke | 89 (43.6) | 65 (40.1) | 24 (57.1) | 3.928 | 0.047 |
| Prior antiplatelet | 41 (20.1) | 36 (22.2) | 5 (11.9) | 2.211 | 0.137 |
| Recurrent AISd | 39 (19.1) | 20 (12.3) | 19 (45.2) | 23.337 | 0.000 |
aα-HBDH, α-hydroxybutyrate dehydrogenase; bOMT, onset to medication time; cbNIHSS, the baseline score of National Institutes of Health Stroke Scale score at registration; dAIS, acute ischemic stroke