Growth and cell cycle profiles of yeast populations in batch cultures under different conditions (C, H, I, and R). (a) Growth curves of the four culture conditions. Vertical dashed lines indicate the separations between the main growth phases: glucose fermentation, diauxic lag phase, respiratory phase, and, finally, stationary phase. (b) Dynamic trends of the control yeast population in the different cell cycle phases (G0, G1, S, and G2/M). (c) Dynamic trends of the yeast population grown with the exhausted medium containing extracellular self-DNA in the different cell cycle phases (G0, G1, S, and G2/M). Data are averages of three biological replicates ± SD.