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. 2024 Jun 20;13(12):1071. doi: 10.3390/cells13121071
ALK anaplastic lymphoma kinase
ATC anaplastic thyroid cancer
CEA carcinoembryonic antigen
CRC colorectal cancer
CTLA-4 cytotoxic T-lymphocyte-associated protein 4
DCs dendritic cells
DCR disease control rate
dMMR mismatch repair-deficient
DOR duration of response
EGFR epidermal growth factor receptor
EML4 EMAP-like 4
FDA United States Food and Drug Administration
FLT3L FMS-like tyrosine kinase 3 ligand
GDF15 growth differentiation factor 15
HER2 human epidermal growth factor receptor 2
HRR homologous recombination repair
IHC immunohistochemistry
InDel insertions and deletions
LIFl leukemia inhibitory factor 1
MAPK Mitogen-activated protein kinase
MCL1 myeloid cell leukemia-1
mDOR median duration of the response
MDSC myeloid-derived suppressor cells
MEK1 and MEK2 mitogen-activated protein kinase 1 and 2
MIP molecular imprinting polymers
MSI-H metastatic microsatellite instability-high
NGR1 HER3-targeting arm to block neuregulin 1
NGS Next-generation sequencing
NK natural killer cell
NPM1 nucleophosmin 1
NSCLC non-small-cell lung cancer
NTRK neurotrophic receptor tyrosine kinase
ORR objective response rate
OS overall survival
PD-1 programmed death receptor 1
PD-L1 programmed death ligand 1
PFS progression-free survival
P-GP P-Glycoprotein
RET rearranged during transfection
ROS1 receptor tyrosine kinase ROS proto-oncogene 1
TAAs tumor-associated antigens
TAMs tumor-ssociated macrophages
TNBC triple-negative breast cancer
TCGA The Cancer Genome Atlas Program
TME tumor microenvironment
TLR Toll-like receptor
TMB-H high metastatic tumor mutational burden