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. 2024 Jun 14;14(6):699. doi: 10.3390/biom14060699

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Antibiofilm activity of melittin and Mel-LX3 against drug-resistant bacteria. (a) Biofilm inhibition by peptides against MRSA. (b) Biofilm inhibition by peptides against MDRPA. (c) Biofilm eradication by peptides against MRSA. (d) Biofilm eradication by peptides against MDRPA. The dashed lines represent the 50% and 90% inhibition and eradication concentrations. Visualization of antibiofilm properties of the peptides against (e) MRSA and (f) MDRPA. Live and dead cells are illustrated in green (SYTO 9) and red (PI) fluorescence, respectively.