Table 4.

Summary.

VMAT-2, which transports dopamine into monoaminergic vesicles, forms a kind of complex with tyrosine hydroxylase and aromatic enzyme L-amino acid decarboxylase that prevents the existence of free dopamine during dopamine synthesis.

VMAT-2 forms a kind of complex with the dopamine transporter and syn-aptogyrin-3 that prevent the existence of free dopamine in the cytosol during its reuptake after neurotransmission.

There is an inverse relationship between neuromelanin levels and VMAT-2 ex-pression