Table 3.
Bacterial and viral co-colonization in study participants at baseline
| HCLD + group % (n/N) |
HCLD—group % (n/N) |
Pa | |
|---|---|---|---|
| Bacterial detection | |||
| Single bacterial species | 61% (175/287) | 43.1% (25/58) | 0.013 |
| At least 2 bacterial species | 35.9% (103/287) | 19% (11/58) | 0.014 |
| > 2 bacterial species | 21.3% (61/287) | 12.1% (7/58) | 0.147 |
| Bacterial co-colonization | |||
| SP & SA | 2.4% (7/287) | 3.4% (2/58) | 0.651 |
| SP & HI | 30% (86/287) | 12.1% (7/58) | 0.005 |
| SP & MC | 20.9% (60/287) | 12.1% (7/58) | 0.146 |
| SA & HI | 2.1% (6/287) | 1.7% (1/58) | 1.000 |
| SA & MC | 1.1% (3/287) | 3.5% (2/58) | 0.198 |
| MC & HI | 18.8% (54/287) | 12.1% (7/58) | 0.261 |
| SP & other bacterial species a | 4.9% (14/287) | 3.5% (2/58) | 1.000 |
| MC & other bacterial species a | 3.1% (9/287) | 1.7% (1/58) | 1.000 |
| HI & other bacterial species a | 5.2% (15/287) | 3.5% (2/58) | 0.748 |
| SA & other bacterial species | 3.1% (9/287) | 0% (0/58) | 0.366 |
| Virus detection | |||
| Single virus | 8.0% (23/287) | 0% (0/58) | 0.019 |
| ≥ 2 viruses | - | - | - |
| Viral and bacterial co-detection | |||
| Single virus + single bacterial species | 6.6% (19/287) | 0% (0/58) | 0.053 |
| Single virus + multiple bacterial species | 5.6% (16/287) | 0% (0/58) | 0.084 |
Other bacteria a; bacteria analyzed as one group (Klebsiella pneumoniae, Neisseria meningitidis, Acinetobacter baumanii and Bordetella pertussis/holmesii, HI type B, S. oralis, N. lactamia & S. pyogens); pa, Fisher's exact test