ALAT	Alanine aminotransferase
ASAT	Aspartate aminotransferase
BFM	Body fat percentage
BMI	Body mass index
BSA	Body surface area
BW	Bodyweight
CL	Clearance
Cmin	Minimum concentration
CrCL	Creatinine clearance
CYP	Cytochrome P
FFM	Fat-free mass
IIV	Inter-individual variability
ka	Absorption rate constants
MAPK/ERK	Mitogen-activated protein kinase/extracellular-regulated kinase
MEK	Mitogen-activated protein kinases
Nonmem	Nonlinear mixed effect modelling
OpTAT	Optimizing oral Targeted Anticancer Therapies
PAL	Alkaline phosphatase
pcVPC	Prediction-corrected visual predictive check
PK	Pharmacokinetics
popPK	Population pharmacokinetic
PsN	Pearl speaks Nonmem
Q	Intercompartmental clearance
RSE	Relative standard error
TDM	Therapeutic drug monitoring
Tmax	Time required to reach maximum concentration
V2	Central volume
V3	Peripheral volume
ΔOFV	Difference in objective function values
95% PI	95% prediction interval