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. 2024 Jun 18;12(6):1352. doi: 10.3390/biomedicines12061352

Table 1.

Differences between patients with sporadic and familial PHEO. Univariate analysis.

Variable Sporadic Family OR (95% CI) p-Value
Female sex 32 (44.4%) 40 (55.6%) 1 0.019
Male sex 16 (25%) 48 (75%) 2.40 (1.15–4.99)
Age 50.39 ± 14.74 years 36.32 ± 12.39 years 0.93 (0.90–0.96) <0.001
Bilaterality <0.001
No 42 (60%) 28 (40%) 1
Yes 6 (9.1%) 60 (90.9%) 15.00 (5.71–39.41)
BP-related symptoms <0.001
No 12 (16.4%) 61 (83.6%) 1
Yes 36 (57.1%) 27 (42.9%) 0.15 (0.07–0.33)
Cardiological symptoms 0.001
No 24 (25.8%) 69 (74.2%) 1
Yes 24 (55.8%) 19 (44.2%) 0.28 (0.13–0.59)
Neurological symptoms 0.012
No 27 (28.4%) 68 (71.6%) 1
Yes 21 (51.2%) 20 (48.8%) 0.38 (0.18–0.81)
Skin symptoms 0.009
No 30 (29.1%) 73 (70.9%) 1
Yes 18 (54.5%) 15 (45.5%) 0.34 (0.15–0.77)
Adrenergic profile 0.568
No 36 (35.6%) 65 (64.4%) 1
Yes 9 (30%) 21(70%) 1.29 (0.54–3.12)
Noradrenergic profile 0.915
No 38 (34.5%) 72 (65.5%) 1
Yes 7 (33.3%) 14 (66.7%) 1.06 (0.39–2.84)
Dopaminergic profile 0.644
No 44 (34.1%) 85 (65.9%) 1
Yes 1 (100%) 1 (50%) 0.52 (0.03–8.48)
Mixed profile 0.018
No 19 (25.7%) 55 (74.3%) 1
Yes 26 (45.6%) 31 (54.4%) 0.41 (0.20–0.86)
Normal profile 0.276
No 44 (35.5%) 80 (64.5%) 1
Yes 1 (14.3%) 6 (85.7%) 3.30 (0.39–28.29)
Mixed dopaminergic profile 0.42
No 17 (50%) 17 (50%) 1
Yes 9 (39.1%) 14 (60.9%) 1.56 (0.53–4.55)
PASS scale 3.95 ± 2.59 3.04 ± 2.17 0.85 (0.65–1.10) 0.213
Size 4.55 ± 3.24 cm 3.04 ± 1.89 cm 0.79 (0.67–0.92) 0.002