BRD	Bromodomain: A protein domain found in certain proteins that recognize acetylated lysine residues in histones, playing a role in gene regulation.
CBP	CREB-binding protein: A transcriptional coactivator that regulates gene expression by interacting with various transcription factors.
CD4 T cell	Helper T cell expressing CD4 receptor: A type of T lymphocyte that orchestrates immune responses by activating other immune cells, particularly B cells and macrophages.
CD8 T cell	Cytotoxic T cell expressing CD8 receptor: A type of T lymphocyte that directly kills infected or abnormal cells by releasing cytotoxic molecules.
H3K27ac	Histone H3 Lysine 27 acetylation: A histone modification associated with active gene transcription.
GATA3	GATA-binding protein 3: A transcription factor important for the development and function of T cells, particularly Th2 cells.
IFNγ	Interferon-gamma: A cytokine produced by activated T cells and natural killer cells that plays a critical role in immune responses against viruses, intracellular bacteria, and tumors.
IL2	Interleukin-2: A cytokine produced by activated T cells that stimulates the growth and differentiation of T cells and other immune cells.
IL4	Interleukin-4: A cytokine produced by activated T cells, mast cells, and basophils that promotes the differentiation of naive T cells into Th2 cells and the production of antibodies by B cells.
IL17α	Interleukin-17α: A cytokine produced by certain T cells that mediates inflammation and is associated with autoimmune diseases.
iCBP112	A P300/CBP specific inhibitor.
JIA	Juvenile Idiopathic Arthritis: A chronic inflammatory disease affecting children that causes joint pain, swelling, and stiffness.
Jurkat cells	A human T lymphocyte cell line used in research to study T cell leukemia, HIV infection, and the immune system.
oJIA	Oligoarticular Juvenile Idiopathic Arthritis, a JIA subtype characterized by joint inflammation, in typically fewer than five joints, during the first six months of the disease.
NFAT	Nuclear factor of activated T cells: A family of transcription factors important for the immune response and other cellular processes.
PBMCs	Peripheral blood mononuclear cells: A type of blood cell containing a single round nucleus, including lymphocytes and monocytes.
P300	E1A-binding protein P300: A histone acetyltransferase and transcriptional coactivator involved in the regulation of gene expression.
ROR-γt	Retinoic acid receptor-related orphan receptor gamma t: A transcription factor that regulates the development and function of certain immune cells, including Th17 cells.
SF	Synovial Fluid of knee joint: Fluid found in the knee joint that lubricates and nourishes the articular cartilage.
SE	Super enhancers: Clusters of enhancers that drive the expression of genes involved in cell identity and disease.
shRNA	Short hairpin RNA: A sequence of RNA that makes a tight hairpin turn and can be used to silence gene expression.
T-BET	T-box transcription factor TBX21: A transcription factor important for the development and function of Th1 cells and cytotoxic T cells.
TFs	Transcription factors: Proteins that bind to DNA and regulate the transcription of genes by controlling the initiation of RNA synthesis.
HAT	Histone acetyltransferase: An enzyme that adds acetyl groups to histone proteins, affecting chromatin structure and gene expression.