Table 3.

Meta-regression: Association of treatment and proportion of complications.

Variable	Association with Outcome		Model Fit		Heterogeneity among Studies
	Coefficient (95% CI)	p	R2	p *	I2 (%)	H2	τ2	p **
Treatment	−0.06 (−0.20 to 0.09)	0.459	0	0.450	91	11	0.05	<0.001
Treatment	−0.06 (−0.21 to 0.08)	0.413	1	0.299	90	10	0.05	<0.001
Year ≥ 2015	0.09 (−0.04 to 0.22)	0.175
Treatment	−0.04 (−0.20 to 0.11)	0.599	0	0.617	90	10	0.05	<0.001
# Patients ≥ 50	0.06 (−0.13 to 0.25)	0.540
Treatment	−0.05 (−0.21 to 0.10)	0.522	0	0.457	90	10	0.05	<0.001
Year ≥ 2015	0.09 (−0.05 to 0.22)	0.203
# Patients ≥ 50	0.04 (−0.14 to 0.23)	0.654

* p of regression model testing whether explanatory variables are associated with dependent variable. ** p of Cochran’s Q test of residual homogeneity testing the H₀ that all study results are equal. # number