Table 3.
Performance of the MCR score as a predictor of MACEs using 503 patients with peripheral artery disease.
| Events | Low Risk (N = 100) |
Moderate Risk (N = 115) |
High Risk (N = 140) |
Very High Risk (N = 148) |
|---|---|---|---|---|
| Major adverse cardiovascular events (MACEs) | ||||
| #MACEs (%) | 3 (3) | 13 (11.30) | 16 (11.43) | 17 (11.49) |
| Crude HR (95% CI) | 1 | 3.52 (1.00–12.12) | 4.18 (1.22–14.36) | 5.08 (1.49–17.36) |
| p value | 0.048 * | 0.023 * | 0.009 * | |
| Multivariate adjusted HR (95% CI) | 1 | 2.57 (0.55–9.31) | 3.51 (0.78–15.86) | 4.67 (1.03–21.09) |
| p value | 0.231 | 0.102 | 0.045 * | |
| Major adverse limb events (MALEs) | ||||
| # MALEs (%) | 31 (31) | 49 (42.60) | 63 (45) | 50 (33.78) |
| Crude HR (95% CI) | 1 | 1.33 (0.85–2.09) | 1.55 (1.01–2.38) | 1.21 (0.77–1.89) |
| p value | 0.213 | 0.046 * | 0.398 | |
| Multivariate adjusted HR (95% CI) | 1 | 1.29 (0.81–2.33) | 1.66 (1.04–3.2) | 1.34 (0.79–2.94) |
| p value | 0.30 | 0.039 * | 0.249 | |
| Major adverse limb and cardiac events (MALEs + MACEs) |
||||
| #MALEs + MACEs (%) | 34 (34) | 57 (49.57) | 70 (50) | 63 (42.57) |
| Crude HR (95% CI) | 1 | 1.37 (0.89–2.09) | 1.58 (1.05–2.37) | 1.41 (0.93–2.14) |
| p value | 0.145 | 0.029 * | 0.107 | |
| Multivariate adjusted HR (95%CI) | 1 | 1.35 (0.85–2.13) | 1.6 (1.01–2.53) | 1.46 (0.92–2.30) |
| p value | 0.204 | 0.045 * | 0.108 |
Multivariate model adjusted by factors that were found significant in Tables S2 and S3 for MACEs, MALEs, and MALEs + MACEs. Multivariate models were adjusted by coronary artery disease, coronary artery bypass graft (CABG), chronic obstructive pulmonary disorder, myocardial infarction, chronic kidney disease, hemodialysis, peritoneal dialysis, creatinine, and atrial fibrillation. *: significant with p-value < 0.05.