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. 2024 Jun 14;46(6):5984–5998. doi: 10.3390/cimb46060357

Figure 5.

Figure 5

Effects of carotenoids on the mRNA expression of Nrf2 and Nrf2-target genes in SH-SY5Y cells. Cells were treated for 24 h with the studied carotenoids (5 µM). At the end of treatment, Nrf2 (A), NQO1 (B), and GSTP1 (C) gene expressions were determined using RT-PCR. Data are expressed as relative mRNA expression and shown as mean ± SD of three independent experiments (°°° p < 0.001 vs. cells treated with fucoxanthin; * p < 0.05 and *** p < 0.001 vs. untreated cells, one-way ANOVA with Tukey post hoc test).