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. 2024 May 21;10(6):352. doi: 10.3390/gels10060352

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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The proliferation of A549/Jurkat cells is determined by MTS assay. (A) The IC₅₀ of nivolumab-loaded GNPs showed a significant decrease at various time intervals. (B) Displays a significant change in IC₅₀ for free nivolumab solution at different concentrations and time intervals. (C) Shows a significant difference (**** p < 0.0001, *** p = 0.0007) between the loaded and free nivolumab. (D) Displays a significance difference (**** p < 0.0001) when comparing the % viability of nivolumab-loaded GNPs with free nivolumab solution using one-way ANOVA.