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. 2024 Jun 19;15(6):809. doi: 10.3390/genes15060809

Figure 2.

Figure 2

This figure shows the domain structure of the RASGRF2 protein (modified from Nair and Saha et al., 2023 [17]). The domains from left to right are Pleckstrin Homology domain 1 (PH1), Coiled Coil domain (CC), ilimaquinone domain (IQ), Dbl Homology domain (DH), Pleckstrin Homology domain 2 (PH2), Immunoreceptor Tyrosine-based Inhibition Motif (ITIM), Ras Exchanger Motif (REM), Cyclin Destruction Box (CDB), and CDC25 Homology domain (CDC25). The OGM breakpoint region (OGM BR, exons 10–12) is located within the PH2 domain.