Table 1.
Baseline characteristics of the 41 study participants.
| Variable | Total (n = 41) |
aSDH Group (n = 21) |
cSDH Group (n = 20) |
p * |
|---|---|---|---|---|
| Demographic characteristics | ||||
| Age, years | ||||
| mean (SD) | 65.9 (14.3) | 58.6 (14.8) | 73.2 (9.4) | <0.0001 |
| median (IQR) | 64 (19) | 57 (12) | 74 (9.5) | |
| Sex | ||||
| male | 31 | 17 | 14 | 0.717 |
| female | 10 | 4 | 6 | |
| Clinical characteristics | ||||
| GCS, median (IQR) | 14 (3) | 12 (9) | 14.5 (2) | 0.005 |
| presence of paresis, n | 24 | 15 | 9 | 0.061 |
| presence of anisocoria, n | 7 | 7 | 0 | - |
| speech impairment, n | 22 | 14 | 8 | 0.121 |
| Radiological features, median (IQR) | ||||
| hematoma volume, cc | 124.4 (90.2) | 123.4 (84.4) | 125.3 (90.2) | 0.223 |
| midline shift, mm | 8.8 (8) | 8.5 (5.7) | 9.5 (6.1) | 0.940 |
| hematoma density, HU | 40 (29) | 61 (9) | 32.5 (12) | <0.0001 |
| Aquaporin plasma concentration, median (IQR) | ||||
| AQP1, ng/mL | 2.81 (0.79) | 2.82 (0.79) | 2.60 (0.91) | 0.494 |
| AQP2, ng/mL | 3.60 (1.38) | 3.79 (1.45) | 3.45 (1.21) | 0.452 |
| AQP4, ng/mL | 1.39 (0.56) | 1.38 (0.57) | 1.39 (0.45) | 0.847 |
| AQP9, ng/mL | 2.47 (0.82) | 2.50 (0.76) | 2.40 (0.68) | 0.452 |
Abbreviations: SD—standard deviation; IQR—interquartile range; SDH—subdural hematoma; GCS—Glasgow Coma Scale; cc—cubic centimeters; mm—millimeters; HU—Hounsfield units; and p *—Mann–Whitney U test (for quantitative data) or χ2 test (for qualitative data). Baseline characteristics of the 48 study participants.