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. 2024 Jun 13;25(12):6539. doi: 10.3390/ijms25126539

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Gut–Skin axis in AD. Changes in the composition of gut and skin microbiota related to interacting with each other through signaling pathways. Decreased (↓) activity of intestinal commensals: Lactobacillus, Bifidobaterium, Akkermansia, Corynebacterium and F.prausnitzii, and an increase (↑) in the activity of other intestinal residents: E.coli, Clostridium difficile and Bacteroides, causes a disruption in the transmission of signaling pathways which affects the structure of the skin microbiota.