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Population, intervention, comparison, and outcome (PICO) research strategy used.
| Parameter | Description |
|---|---|
| Population (P) | Adult patients (age 18+) with heart failure |
| Intervention (I) | Hematopoietic stem cell therapy |
| Comparison (C) | Hematopoietic stem cell therapy or placebo or pre-therapy (baseline) measures or post-therapy measures |
| Outcome (O) | Peak VO2, New York Heart Association (NYHA) symptom class, major adverse cardiovascular events, ejection fraction, duration of follow-up appointments |
