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. 2024 Jun 14;25(12):6577. doi: 10.3390/ijms25126577

Figure 3.

Figure 3

(A) ACC electrophysiological recording with 5-, 10-, and 20-fold CSD amplitude to nociceptive responses in the control, CPSP, and P2X7/CPSP groups (n = 7 per group). (B) Serials of CSD amplitude (mv2/mm2) and (C) CSD peak latency (ms) in ACC with 5-, 10-, and 20-fold basic stimulation strength electric stimulation on the sciatic nerve for the control, CPSP, and P2X7/CPSP groups. ACC: anterior cingulate cortex; CSD: current source density. P2X7/CPSP: P2X7 receptor knock-out mice that induced the CPSP symptoms. * p < 0.05 indicates significant differences.