Figure 5.

Effect of muscimol, a GABA agonist, on the control, CPSP, and P2X7/CPSP groups. Multiunit numbers per minute were measured after muscimol application for the (A) control, (B) CPSP, and (C) P2X7/CPSP groups over 180 min. (D) Multiunit numbers per minute were assessed for the control, CPSP, and P2X7/CPSP groups (n = 6 per group) during the spontaneous and muscimol application phases. P2X7/CPSP: P2X7 receptor knock-out mice that induced the CPSP symptoms. Note, different color of lines indicates different electrical channels. n.s.: nonsignificant differences. * p < 0.05 indicates significant differences.