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. 2024 Jun 14;25(12):6577. doi: 10.3390/ijms25126577

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© 2024 by the authors.

Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).

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Overexpression of the P2X4 receptor after VBC lesions did not occur in P2X7 KO mice. (A) Examples of Western blotting results for P2X4 of the control, CPSP, and P2X7/CPSP groups. Note that monomeric P2X4 is distributed at 50 kDa and its dimeric form is at ~100 kDa. (B) Ratio to tubulin for 50 kDa and 100 kDa dominated bands for the P2X4 receptor in the control, CPSP, and P2X7/CPSP groups (n = 8 per group). n.s.: nonsignificant difference; *: significant difference. P2X7/CPSP: P2X7 receptor knock-out mice that induced the CPSP symptoms.