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. 2024 Jun 20;25(12):6766. doi: 10.3390/ijms25126766

Table 3.

Summary of the contradicting literature on the onset of different learning and memory impairments in 5xFAD mice.

Early Onset
(1–3 Months)
Mid-Onset
(4–8 Months)
Late-Onset
(9–18 Months)
Absence
Impaired visual recognition memory - [53,93,94,95,96,97,99,101,102,103,104] [51,98,100] [58]
Impaired associative learning and memory - [60,107,108,109,110,111,113,114] [48,112] [40]
Impaired spatial working memory [128] [33,41,44,46,54,63,118,119,120,122,123,124,126] [51,58,59,117,121,125] [45,61,103]
Impaired spatial reference learning and memory [120,130,131,132] [60,66,77,97,99,103,107,114,122,123,124,126,133,134,135,136] [47,48,49,50,58,59,112,121,137,138,139] [45]