Table 6.
ACR/EULAR definition of obstetric APS criteria.
| Clinical Domains | Weight | Laboratory Domains | Weight |
|---|---|---|---|
| ≥3 consecutive pre-fetal deaths (<10th GW) and/or ≥3 early fetal deaths (10th–16th GW) | 1 | Positive LAC (single, one time) | 1 |
| ≥1 fetal death (16th–33rd GW) without severe PE or severe PI | 1 | Positive LAC (persistent) | 5 |
| Severe PE or PI with or without fetal death (<34th GW) | 3 | Moderate or high positive IgM aCL and/or aβ2GP | 1 |
| Severe PE and PI with or without fetal death (<34th GW) | 4 | Moderate positive IgG aCL and/or aβ2GP | 4 |
| High positive IgG aCL or aβ2GP | 5 | ||
| High positive IgG aCL and aβ2GP | 7 |
Legend: a-β2GPI: anti-beta2-glycoprotein I antibodies; aCL: anticardiolipin antibodies GW: gestational week; LAC: lupus anticoagulant PE: preeclampsia; PI: placenta insufficiency.