Table 1.
Characteristics of Mycoplasma pneumoniae-infected patients admitted to the intensive care unit.
| Total | |
|---|---|
| Age (years) [median (IQR) | 44.0 (29.0 to 62.0) |
| Sex (female) | 3 (17.6) |
| BMI (kg/m2) median (IQR) | 26.3 (22.4 to 28.5) |
| Cardiovascular disease | 4 (23.5) |
| Preexisting respiratory disease (COPD, etc.) | 2 (11.8) |
| Chronic renal insufficiency | 1 (5.9) |
| Neurological disorder | 1 (5.9) |
| Malignancy | 1 (5.9) |
| Diabetes Mellitus | 2 (11.8) |
| Auto-immune disease | 2 (11.8) |
| Immune suppression | 1 (5.9) |
| Smoking (current or previous) | 6 (35.3) |
| Harddrugs use | 2 (11.8) |
| Hypoxia as the reason for ICU admission | 14 (82.4) |
| Hemodynamic instability as a reason for ICU admission | 3 (17.6) |
| APACHE score on admission [median (IQR) | 45.0 (37.0 to 52.0) |
| SAPS II on admission median (IQR) | 21.0 (18.0 to 24.0) |
| Leukocyte on admission (×109/L) median (IQR) | 11.3 (9.2 to 17.1) |
| CRP (mg/L) on presentation median (IQR) | 169 (102 to 304) |
| Non-invasive ventilation including high flow | 13 (76.5) |
| Duration of non-invasive ventilation (hours/days) median (IQR) * | 72 (24–108) 3 (1–4.5) |
| Invasive mechanical ventilation (IMV) | 5 (29.4) |
| Duration of invasive mechanical ventilation (IMV) (days) median (IQR) † | 6.0 (4.0 to 9.0) |
| Highest FIO2 (%) median (IQR)] | 75.0 (60.0 to 85.0) |
| Lowest PaO2 (kPa) at admission under maximal FIO2 median (IQR) | 9.0 (8.2 to 10.1) |
| Lowest PF ratio (mmHg) in mechanically ventilated patients median (IQR) ‡ | 85.0 (77 to 110) |
| Highest PaCO2 (kPa) median (IQR) | 6.0 (5.2 to 6.4) |
| SpO2 at admission ICU with oxygen suppletion median (IQR) | 93.0 (92.0 to 95.0) |
| FIO2 at admission ICU median (IQR) | 70.0 (60.0 to 90.0) |
| ROX-score (pulse oximetry/FIO21) at admission ICU median (IQR) | 5.6 (4.6 to 13.1) |
| Highest PEEP (cmH2O) median (IQR) § | 14.0 (12.0 to 14.0) |
| Highest driving pressure (cmH2O) median (IQR) ¶ | 15.0 (13.8 to 16.8) |
| Lowest pH median (IQR) | 7.4 (7.3 to 7.4) |
| Proning | 3 (17.6) |
| AKI during ICU stay | 2 (11.8) |
| Steroid treatment | 7 (41.2) |
| Duration of doxycycline treatment (days) median (IQR) ** | 14.0 (7.0 to 14.0) |
| Duration of azithromycin treatment (days) median (IQR) †† | 5.0 (3.5 to 5.0) |
| Duration of hospital admission (days) median (IQR) | 10.0 (7.0 to 14.0) |
| Duration of intensive care admission (days) median (IQR) | 5.0 (2.0 to 7.0) |
Data were presented as numbers and percentages or indicated otherwise. IQR: interquartile range. Data were available for n patients: *: 13 patients, †: 5 patients, ‡: 7 patients, §: 5 patients, ¶: 4 patients, **: 14 patients, ††: 6 patients. None received renal replacement therapy. Mortality was 0% in this retrospective cohort.