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Replication-competent viruses tested for gene delivery to DRGs. In each case the indicated genes have been inactivated, with insertion of a chimeric LAP1-MMLV-lacZ promoter cassette either in the gene encoding vhs (UL41) or in UL43 as indicated by the arrowhead. This insertion forms the pR8c cassette when inserted in UL43 and the pR15 cassette when inserted in vhs.
