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. 2024 Jun 22;17:2477–2489. doi: 10.2147/PRBM.S460393

Table 3.

The Effect of Peer Relationships on Adolescent Loneliness: The Mediation of Psychological Resilience and the Moderation of rs53576 Polymorphism in the OXTR Gene

Variables Model 1 (Dependent Variable: Loneliness) Model 2 (Dependent Variable: Psychological Resilience) Model 2 (Dependent Variable: Loneliness)
β t p 95% CI β t p 95% CI β t p 95% CI
Gender 0.25 3.40** < 0.01 [0.10,0.39] −0.36 4.91*** <0.001 [−0.50,-0.21] 0.25 3.48*** < 0.01 [0.11, 0.39]
X −0.30 −7.72*** < 0.001 [−0.38, −0.23] 0.55 10.07*** < 0.001 [0.44, 0.66] −0.31 −7.89*** < 0.001 [−0.39,-0.23]
W1 0.10 1.26 0.21 [−0.05, 0.24] 0.08 1.01 0.31 [−0.07, 0.22]
W2 0.14 1.09 0.28 [−0.11, 0.38] 0.08 0.66 0.51 [−0.16, 0.32]
XW1 −0.22 −2.86 0.004 [−0.37, −0.07]
XW2 −0.23 −1.90 0.06 [−0.47, 0.01]
M −0.26 −6.56*** < 0.001 [−0.34,-0.18] −0.21 −3.93*** < 0.001 [−0.32,-0.11]
M*W1 −0.04 −0.57 0.57 [−0.19, 0.10]
M*W2 −0.29 −2.35* 0.019 [−0.52, −0.05]
R2 0.24 0.21 0.25
F 63.777*** 27.56*** 28.41***

Notes: X = peer relationships; W1 = GA vs AA; W2 = GG vs AA; XW1 is the interaction term between peer relationships and rs53576 being virtualized as W1; XW2 is the interaction term between peer relationships and rs53576 being virtualized as W2; M = psychological resilience; M*W1 is the interaction term between psychological resilience and rs53576 being virtualized as W1; M*W2 is the interaction term between psychological resilience and rs53576 being virtualized as W2; bolded font indicates the value is significant, *p < 0.05, **p < 0.01, ***p < 0.001.