Grade	Allergic-like	Physiologic
Mild: self-limiting without evidence of progression	limited urticaria, cutaneous edema, limited “scratchy” throat, nasal congestion, conjunctivitis	Limited nausea, transient flushing, headache, mild hypertension, spontaneous vasovagal reaction
Moderate: pronounced symptoms that usually require medical attention	Diffuse urticaria, diffuse erythema, stable vital signs, throat tightness w/o dyspnea, bronchospasm, mild to no hypoxia	Protracted nausea, hypertensive urgency, isolated chest pain, vasovagal reaction requiring and responding to treatment
Severe: Often life-threatening and can result in death or permanent morbidity	Diffuse edema with dyspnea, Diffuse erythema with hypotension, laryngeal edema with stridor and/or hypoxia, bronchospasm, anaphylactic shock	Vasovagal reaction resistant to treatment, arrhythmia, convulsions, seizures, hypertensive emergency