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. 2024 Jun 5;17(6):733. doi: 10.3390/ph17060733

Figure 5.

Figure 5

Effect of different oils on the skin tissue contents of (A) TNF-α, (B) NF-κB, and (C) NLRP3 as inflammatory markers in addition to serum levels of (D) CX-43 as a skin integrity marker in wound-injured rats. Statistical analysis was achieved with one-way ANOVA and subsequent multiple comparisons using Tukey’s test. Data are expressed as the mean ± SD [n = 6] with p-value < 0.05 as compared with the normal control group (α) and the wound injury (β), wound injury + PSO/ST (γ), wound injury + HSO (φ), and wound injury + CSO (ε) groups. [F-value of TNF-α = 198.9, F-value of NF-κB = 139.8, F-value of NLRP3 = 253.5, and F-value of CX-43 = 423.8.] CX-43; connexin-43, CSO; Cantaloupe seed oil, HSO; Honeydew melon seed oil, NLRP3; NLR family pyrin domain containing 3, NF-κB; nuclear transcription factor kappa B, PSO; pumpkin seed oil, ST; standard, TNF-α; tumor necrosis factor-alpha, ZSO; Zucchini seed oil.