Table 2.

PERMANOVA results for Bray–Curtis dissimilarity by CID (accounting for repeated measures) applied on overall 16S rRNA gene amplicon sequencing data and subsets.

		Sex		Diet		Glycaemic Status		Diet × Glycaemic Status
								HP-NB		HC-CB
	All	Male	Female	HP-NB	HC-CB	N	P	N	P	N	P
n	84	38	46	38	46	52	32	23	15	29	17
R2	0.004	0.012	0.007	0.007	0.007	0.008	0.007	0.012	0.014	0.019	0.021
p-value	0.447	0.017	0.73	0.31	0.821	0.107	0.995	0.471	0.903	0.077	0.548

Subsets were defined based on three factors: sex (male, female), diet (HP-NB, higher-protein nut bar; HC-CB, higher-carbohydrate cereal bar), and glycaemic status (N, normoglycaemia; P, prediabetes). The table presents the results for all possible combinations of factors, including overall effect, effect within each sex level, diet level, and glycaemia level, and effect within each glycaemia level when stratified by diet. Significant p-values (p < 0.05) are shown in bold type.