Table 3.
Renal oxidative stress and inflammation parameters.
| Group | LPO mmol/mg Tissue | GSH µg/g Tissue |
GST µmol/min/mg pt | SOD U/mg pt | CAT µmol/min/mg | NAG mD.O/mg pt | MPO mD.O/mg pt | |
|---|---|---|---|---|---|---|---|---|
| NTRs | VEH | 4.53 ± 0.26 | 1267.16 ± 92.48 | 0.44 ± 0.30 | 4.32 ± 0.84 | 59.48 ± 12.50 | 113.75 ± 20.93 | 5.26 ± 1.04 |
| VEH+EG/AC | 4.32 ± 0.13 | 1524.96 ± 131.45 | 0.45 ± 0.20 | 4.98 ± 1.68 | 19.94 ± 5.93 b | 83.04 ± 14.76 b | 3.54 ± 1.02 | |
| HCTZ+EG/AC | 4.61 ± 0.20 | 1705.35 ± 99.57 b | 0.23 ± 0.01 | 5.83 ± 0.47 | 40.03 ± 2.89 a,b | 75.35 ± 10.11 b | 3.00 ± 0.25 b | |
| RA+EG/AC | 4.39 ± 0.28 | 1480.76 ± 258.07 | 0.33 ± 0.23 | 4.92 ± 1.15 | 26.76 ± 7.92 b | 89.29 ± 15.24 | 3.65 ± 1.47 | |
| SHRs | VEH | 4.45 ± 0.29 | 1111.49 ± 71.06 | 0.30 ± 0.08 | 3.55 ± 0.51 | 35.54 ± 17.74 | 82.16 ± 15.62 | 3.11 ± 0.55 |
| VEH+EG/AC | 4.53 ± 0.34 | 1410.36 ± 129.83 b | 0.29 ± 0.11 | 4.25 ± 1.49 | 13.29 ± 12.26 | 109.86 ± 31.41 | 4.01 ± 1.43 | |
| HCTZ+EG/AC | 4.17 ± 0.15 | 741.68 ± 145.62 a,b | 0.73 ± 0.33 a,b | 5.11 ± 0.80 | 41.23 ± 12.31 | 100.97 ± 26.67 | 4.87 ± 1.59 | |
| RA+EG/AC | 4.42 ± 0.20 | 1261.86 ± 129.83 | 0.70 ± 0.24 a,b | 5.75 ± 0.81b | 57.89 ± 20.50a | 117.88 ± 23.05 | 5.16 ± 1.59 |
Values expressed in mean ± standard deviation; a: p < 0.05 compared with the VEH+EG/AC group; b: p < 0.05 compared with the VEH group.