Table 4.
Liver oxidative stress and inflammation parameters.
| Group | LPO mmol/mg Tissue | GSH µg/g Tissue | GST µmol/min/mg pt | SOD U/mg pt | CAT µmol/min/mg | NAG mD.O/mg pt | MPO mD.O/mg pt | |
|---|---|---|---|---|---|---|---|---|
| NTRs | VEH | 3.89 ± 0.04 | 1043.98 ± 75.66 | 0.79 ± 0.14 | 4.67 ± 0.34 | 7.30 ± 6.05 | 96.24 ± 17.48 | 5.44 ± 0.68 |
| VEH+EG/AC | 3.88 ± 0.10 | 749.56 ± 145.98 b | 0.29 ± 0.19 b | 3.17 ± 0.75 b | 23.07 ± 9.63 b | 52.29 ± 10.93 b | 4.43 ± 0.87 | |
| HCTZ+EG/AC | 4.07 ± 0.13 a,b | 1188.18 ± 205.62 a | 0.42 ± 0.13 b | 3.90 ± 0.33 | 21.79 ± 4.31 | 61.58 ± 6.44 b | 3.93 ± 0.81 b | |
| RA+EG/AC | 3.61 ± 0.12 a,b | 1343.79 ± 222.12 a,b | 0.45 ± 0.17 b | 4.59 ± 0.68 a | 26.30 ± 9.40 b | 55.04 ± 11.16 b | 4.47 ± 0.89 | |
| SHRs | VEH | 4.14 ± 0.31 | 1318.91 ± 244.04 | 0.62 ± 0.18 | 3.43 ± 0.32 | 4.58 ± 2.60 | 61.84 ± 12.11 | 5.17 ± 0.94 |
| VEH+EG/AC | 3.80 ± 0.14 b | 2385.20 ± 298.30 b | 0.70 ± 0.15 | 3.86 ± 0.50 | 19.41 ± 7.65 b | 61.68 ± 7.80 | 5.19 ± 1.03 | |
| HCTZ+EG/AC | 3.71 ± 0.17 b | 1682.13 ± 392.97 a | 0.37 ± 0.21 a | 5.79 ± 1.94 a,b | 9.01 ± 4.83 | 65.13 ± 14.47 | 6.38 ± 2.30 | |
| RA+EG/AC | 3.73 ± 0.19 b | 1854.99 ± 357.46 | 0.39 ± 0.16 a | 4.51 ± 1.15 | 18.30 ± 7.59 b | 56.38 ± 4.99 | 4.58 ± 0.60 |
Values expressed in mean ± standard deviation; a: p < 0.05 compared with the VEH+EG/AC group; b: p < 0.05 compared with the VEH group.